http://art-of-bioeng.squarespace.com/pelvic-personas daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443576900387-SOEFPN9UDKA12DZ9VP93/image-asset.png Pelvic Personas   This work demonstrates the interesting variations found in our bodies and explores the ways in which one can interpret medical images. Routinely used by radiologists to assess bone health, medical computed tomography (CT) scans also provide much for the imagination, as shown by these images of the pelvis. Variations in the shape of the sacrum bone and patient position produce a plethora of interpretations in the eye of the viewer. One reading of what emerges from deep within the body are faces, their expressions ranging from grotesque horror to cartoonish joy. Many thanks to the Jacqui Hislop-Jambrich and the Victorian Institute of Forensic Medicine for providing these images for our research. http://art-of-bioeng.squarespace.com/highway-to-the-heart daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443652122536-XBDK0QPRC0FFOFL9QMKN/image-asset.png Highway to the Heart   A busy highway of nerves connects the brain with the heart, conveying messages as electrical impulses at break-neck speeds to ensure the heart always pumps enough blood whether one is walking or running. The straights, bridges, off-ramps, and on-ramps you can see are made up of nerves that are less than one tenth the width of a human hair traversing a small volume of muscle. The lights sit at junctions where nerves - when necessary - pass on their cargo of the neurotransmitter noradrenaline and thereby provoke surrounding muscle cells to beat harder. Bright spots are like street lamps on roads close to the surface; dim spots, lamps on distant streets deep in the volume. http://art-of-bioeng.squarespace.com/read-me daily 1.0 2024-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597610341765-NW2UEIAKPUH4OXGEVZME/21-Geoffry.jpg Home https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597382417117-CDT3PMQSIXRI8JMZIDWI/17-Vijay.jpg Home http://art-of-bioeng.squarespace.com/seetheforestforthetrees daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443652742153-XDZPCFESIS51VSAKGBG0/see_the_forest_for_the_trees.png See the Forest for the Trees   The heart has four chambers; two atria, and two ventricles. The left and right atrial appendages are pocket-shaped structures, which sit on top of the ventricles. This image shows the structure of rabbit atrial appendages, which have been captured by a novel micro-computed-tomography (CT) technique. At microscopic scale, the atrial appendage looks like a network - or forest - of highly interconnected cardiac muscle bundles. http://art-of-bioeng.squarespace.com/see-the-forest-for-the-ttrees daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443251638261-O0VK6TEY2PCG0ER3MCI1/muscles_and_bones.png Bone and Muscle   Microscopy is amazing! Pelvic floor muscles are intimately involved in the birth process, and the strain of these muscles during delivery of the fetal head is considerable. The aim of my project was to characterise the muscle bone interface using differential interference contrast microscopy. This technique produced images that allow a comprehensive analysis of the structure of this interface. http://art-of-bioeng.squarespace.com/the-spectiular daily 0.75 2015-09-30 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443653434530-7V66XGOKMPMV6GSCWT9Z/image-asset.png The Spectacular Bone Spicule   Osteoarthritis is a sinister disease! Because cartilage doesn’t contain any nerves, you usually only begin to experience joint pain once your cartilage has become significantly degenerated. We don’t have a good understanding of how the disease develops or what causes it in most cases. This image shows a bone spicule that has grown from the underlying bone into the cartilage. This bone invasion begins early in the disease, before the cartilage has be lost and may help us to understand how the disease progresses. http://art-of-bioeng.squarespace.com/candy-crush-lung-saga daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443650557228-86C3EALJTLENVBKBPQX6/image-asset.png Candy Crush Lung Saga   Lung disease is usually accompanied by changes to the lung’s microstructure. The spongy tissue of a healthy lung is generally considered to be a homogeneous material consisting of millions of alveoli. The localised breakdown of alveolar walls can be an early indicator of a host of diseases. Developing a method for quantifying the heterogeneity of a slice of lung tissue could well be a valuable tool for early disease detection. A computed tomography (CT) scan of a lung can be used to tell the story of how much diversity there is in each region of the lung. Smaller boxes show regions where higher variation occurs. http://art-of-bioeng.squarespace.com/galleries daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384864282-1IHIFGMINO8DCLGT9NKS/20-Zahra.jpg Galleries http://art-of-bioeng.squarespace.com/kaleidoscope daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443581730104-JKVRVUU5MRMVVCVTJ1WD/image-asset.png Kaleidoscope, 3D!   This image combines one of our favourite childhood toys with cutting-edge science; a kaleidoscopic view from a stereoscopic camera. The mechanical properties of soft tissues such as skin convey much information about our health. Stereoscopic (3D) cameras can be used to determine the mechanical properties of soft tissues. We use the recordings further, to develop mathematical models of the deformation of biological tissues. http://art-of-bioeng.squarespace.com/creeping-fingers-of-arthritis daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443177994271-FDODQ9TE3HYD9UOZ4OTI/image-asset.png Creeping Fingers of Arthritis Osteoarthritis is a sinister disease! We don’t have a good understanding of how the disease develops or what causes it in most cases, and individual diagnosis tends to occur as a result of the arrival of pain. Because cartilage doesn’t contain any nerves, you usually only begin to experience joint pain once your cartilage has become significantly degenerated. This image shows a bone spicule (a sharp point of bone) that has grown from underlying bone into hte cartilage adjacent. This bone invasion begins early in the disease, before the cartilage has been lost, and may help us to understand how the disease progresses. http://art-of-bioeng.squarespace.com/bullet-supremacy daily 0.75 2015-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443238662960-94DDOMOANMAW9Q5GEZO4/image-asset.png Bullet Supremacy   When a bullet impacts its target, the majority of the fragments generated spatter forward in the direction of the bullet. However, there is also a smaller portion of fragmentation at the entrance site, travelling back towards the shooter. This retrograde spatter is called backspatter. Due to its reverse-directionality, backspatter can provide important information to solve crimes that cannot be found in normal forward spatter. This still shot of a bullet penetrating a bone simulant captures both the forward and backspatter being generated by a 9 mm full metal jacket bullet, which has a muzzle speed of 350 metres-per-second. http://art-of-bioeng.squarespace.com/starlight daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1445375935375-3YGANAMA6JI1GG3S29IL/starlight.png Starlight   Tracking complex movements is a critical component of research and computer-generated imagery (CGI) in movies. In this case the researchers are interested in capturing the movements of the skin. Fluorescent spheres were used as markers for tracking changes in the shape of soft deformable objects in 3D during indentation. A high-precision micro-robot arm was developed to provide the indentation from down below. The blue illumination helps to highlight the marker positions, which are captured using a set of cameras. http://art-of-bioeng.squarespace.com/hammer-identity daily 0.75 2015-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443238773504-E2TCC5H8PJDEISG882WK/image-asset.png Hammer Identity   When a violent crime happens, forensic scientists need to deduce the causal criminal event from the evidence. To stand the test in a court of law, the inverse calculation requires rigorous experimentation and simulation. This image of a hammer impacting a bloody surface is part of a high speed video, filmed at 4000 frames-per-second. The dynamic movement and behaviour of the blood observed from the video will allow forensic scientists to understand the resulting blood spatter pattern better, and help bring the identity of the criminal into light. http://art-of-bioeng.squarespace.com/cartilage-matrix-ripples daily 0.75 2015-12-22 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443651678232-IQR4L17CJLTYW9LKWKCX/image-asset.png Cartilage Matrix Ripples   Our Experimental Tissue Mechanics Laboratory is studying how cartilage responds to compressive loads relating to joint function. Using a custom designed indenter that contains a central relieft channel it is possible to greatly enchance visualisation of the patterns of micro-level deformation induced by the compressive loading. The image shows the intersecting pattern of oblique shear bands that form in the healthy cartilage matrix, the cells appearing to 'float' in this micro-ocean of complex formation. http://art-of-bioeng.squarespace.com/a-perpetual-motion daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443238316559-LVZESLSUIAZ2M26TZPU5/re-entry A Perpetual Motion Every muscular motion generates a bioelectrical impulse. This can be used to monitor the health of the muscles producing the impulse. When the bioelectrical impulse is disturbed, sometimes it can be driven into a long-lasting loop activity called re-entry, where the bioelectrical impulse ‘loops back onto’ itself. Re-entry is a major problem because it can disrupt the normal rhythm of activities in the gut or the heart. This work shows a mosaic of the initiation and maintenance of a re-entry event. The tile on the top left corner shows the initiation from a point, which morphs into a repetitive re-entry over time. http://art-of-bioeng.squarespace.com/blood-ultimatum daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443238482376-JISSYGQK91DILWJWN1CF/image-asset.png Blood Ultimatum   In crime investigations, understanding how blood spatter patterns are created is often a critical task. This image is a sequential collage from a high speed video (4000 frames per second), where the sequence captures the various stages of the blood droplet splashing into a small pool of blood. Experiments such as this enhance the understanding of blood splatter at crime scenes. The vision of this research is to implement this understanding into a mathematical model, which will ultimately allow efficient and controlled simulations of different criminal scenarios. http://art-of-bioeng.squarespace.com/micro-electronics daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443744558338-EECLWIZHSSN42K393ZZ9/image-asset.png Micro Electronics   Electric circuits are offering more and more possibilities as a means to help diagnose and monitor patient health. For example, devices can be implanted under the skin or within the body to measure physiological signals. To be viable, these devices must be small and reliable. Integrated circuits are electronics at microscopic scales. One thousand micrometers (mm) fit into one millimeter (mm), so a lot of electronics can be packed into a small circuit. This image is a schematic of a 180mm x 140mm circuit I have been designing. Each colour represents a different layer in the circuit, wires, different chemical implants and connections. http://art-of-bioeng.squarespace.com/the-electrifying-gut daily 0.75 2015-09-30 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443656503299-ZJCZ3TRDQHGSOMQBS0VF/electriying_gut.png The Electrifying Gut   Digestion is governed by a series of contractions in the gut, also known as the gastrointestinal (GI) tract. The gut contractions are in turn governed by a series of bioelectrical events known as slow waves, which reflect the highly specialised functions in each portion of the gut. For example, the stomach is responsible for breakdown and storage of food, while intestine is responsible the uptake of nutrients, which is associated with unique slow waves. This image shows three types of slow waves from different portions of the gut: (top): stomach, (middle): intestine, (bottom): colon (large intestine). and the bottom: colonic activity. The three signals are shown to illustrate the propagating nature of the slow waves. http://art-of-bioeng.squarespace.com/confocal daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443577568939-FI6VTJRE0IA96AQPKE8K/image-asset.png Through the Confocal Looking Glass   The human body is comprised of billions of cells, all working in unison to keep us alive. The gastrointestinal tract (gut) is also comprised of a network of different cell types. What you are looking at is a 1x1 mm2 confocal image of the mouse intestine, at a resolution of 0.5 µm per pixel, which has been imaged using two-photon excitation microscopy. The green channel illustrates the crypts in the epithelum, the red channel the capillaries and other cells. The white channel shows the collagen network. http://art-of-bioeng.squarespace.com/bifurcationsfromtheheart daily 0.75 2015-12-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1450319340888-4YOQD8QNCC7TOFVDF4YQ/lunging_heart.png Bifurcations from the Heart   Many important biological structures, including lung airways and blood circulation systems, are effectively networks of bifurcating vessels, where larger vessels repeatedly split into two smaller vessels to fill the space of an organ or body. This picture shows a mathematically generated test model of bifurcating vessels which serendipitously formed heart shapes from various angles, rendered with computer graphics. http://art-of-bioeng.squarespace.com/clock-of-life daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443742621868-S5EEY6L719YEPW6GA2D8/Clock_of_Life.png Clock of Life   The heart is an amazing biological machine; a 'clockwork' which (almost) never fails. Every single muscle cell in this clock works at precisely timed moments in unison to pump blood through the body. This work presents a series of snapshots of a beating heart that were taken using the magnetic resonance imaging (MRI) technique. From these images a doctor can tell a healthy heart from a failing one. In the course of studying the mechanical functions of the failing heart I've come to appreciate the sheer miracle of each well-delivered beat; the miracle of being alive in this very second, and the next. http://art-of-bioeng.squarespace.com/flex-a-rainbow daily 0.75 2015-10-02 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443743843176-70OM1XFGBV9X1QXSAT8A/image-asset.png Flex a rainbow   Flexure or bending of an elastic rubber beam is simple in action, but fascinatingly complex in theoretical and computational mechanics. In order to bend a beam, one of the lateral faces of the beam is under compression while the other lateral face undergoes extension, forming a circular arc shape. The compression and extension of a beam corresponds to the development of internal stresses, which when we take the average of these stresses, a rainbow across the lateral faces is obtained! This average stress profile is important in determining the strength of a material under both compression and extension and found major applications in biomedical engineering industry. http://art-of-bioeng.squarespace.com/mems-spider daily 0.75 2015-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443252157709-35X594PD6G31SCB4P32S/image-asset.png MEMS Spider   Micro-electro-mechanical (MEMS) is technology which deals with very small electronic components, often between 1 to 100 mciro-metre (1 mm = 1,000 micro-metre) in size. At the heart of the MEMS circuits a tiny pressure sensor can be seen. The sensor can be used to conduct biometric recordings in wearable technologies.   http://art-of-bioeng.squarespace.com/rat-alveoli daily 0.75 2015-12-22 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443252009314-BHZM8UYENRWTUHA6TQRX/Rat_Alveoli.png Rat Alveoli   The human lung is made up of 300 million alveoli, each about a quarter of a millimetre in diameter. On inspiration (breathing in) these alveoli fill up with air, and provide an interface to capillaries so that oxygen can diffuse into the blood stream. The size and shape of the alveoli can change either as a result of ageing or due to the onset of disease. These changes alter the mechanics of the patient’s breathing. Therefore, modelling alveolar mechanics is necessary to link microstructural changes to the patient’s breathing patterns. Alveolar models are best represented as ‘space-filling truncated polyhedra’, which look hexagonal in cross-section. http://art-of-bioeng.squarespace.com/hues-of-performance-1 daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443743304231-M0SNFL27B770XPI4PNEO/image-asset.png Hues of Performance   Competitive sprinters dedicate years to developing their muscles for high-speed running. The way that their muscles respond to the hours and hours of intense training varies from athlete to athlete, and highlights what strategies the athlete uses to generate fast movement. In this work, the Magnetic Resonance Imaging (MRI) was used to image the muscles of a number of competitive American sprinters. The size of their muscles were compared to healthy non-athletes. In this image, the strong muscles are depicted in blue, while the weak muscles are depicted in red. http://art-of-bioeng.squarespace.com/contact daily 0.75 2020-08-16 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597610406502-FA7BT5BSO8Z3QFQ6RO5P/21-Geoffry.jpg Contact http://art-of-bioeng.squarespace.com/breathe-free daily 0.75 2015-12-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1446433605618-3NBM5OKQG3ACBJ82LAA9/breathe-free.png Breathe Free   A chronically blocked nose is no fun for anyone. Productive of particular misery, is a condition called chronic rhinosinusitis; an inflammatory disease of the sinuses leading to completely obstructed breathing. In such cases, endoscopic surgery is routinely performed. The surgery is complicated because of presence of nearby organs such as nerves, the eyes, and the brain. Using fundamental engineering principles, we study the degrees of improvement in breathing after surgery. This image shows the anatomy of sinuses inside the nose and traces of air flow inside the sinuses. http://art-of-bioeng.squarespace.com/new-page daily 0.75 2020-08-14 http://art-of-bioeng.squarespace.com/order daily 0.75 2020-08-14 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597382103934-M18UB7F5QY4081BS3Y78/image-asset.jpeg Order http://art-of-bioeng.squarespace.com/life-tree daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631196690-WV3SRK2Y6D0IMD1THJO5/18-Vijay.jpg Life Tree Life Tree Vijayalakshmi Srinivasan, Dane Gerneke, Dr Alys Clark, Dr Jo James Numerous tiny placental vessels form a complex vasculature that meet the demands of a growing baby during pregnancy. The placenta is a multi-talented organ and - thanks to Micro-CT imaging - we are able to capture such tiny vessels at high resolution for better sophisticated analyses of placental anatomy. http://art-of-bioeng.squarespace.com/mask daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631069497-UPW6MOT6JIZ8L233BGBH/13-Dane-crab.jpg Mask Mask Dane Gerneke, Marie Goeritz This image is from a whole fresh paddle crab. Paddle crabs are sensitive to ground vibrations, but how they detect vibrations is not understood, as they do not have ‘ears’. MicroCT Imaging was undertaken to establish if sand grains located within the shell could be a possible mechanism for vibration detection. A major advantage of MicroCT is being able to see the inside story of structural relationships, and it can reveal features without having to dissect samples. http://art-of-bioeng.squarespace.com/99-red-balloons daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630422901-TBQAQI6LTUOCDR0BDFY3/15-Kelly-red.jpg 99 Red Balloons 99 Red Balloons Dr Kelly Burrowes, Billy Bowman and Dane Gerneke The human lung contains around 480 million alveoli. If these were laid flat, they would cover an area equivalent to around 20 king-sized beds. Alveoli are tiny balloon-like structures which bring air to and from the gas exchange surface. This image was made using a scanning electron microscope using a small section of tissue from a rat lung. http://art-of-bioeng.squarespace.com/sheep-shape daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630321081-8BMBX0HJ8GMW5PGL6KQV/08-Vinod.jpg Sheep Shape Sheep Shape Dr Vinod Suresh, Stephen Waite, John Cater, Garry Waghorn A sheep eats about 10 kg of grass every day, which is digested by the microorganisms in its rumen – the first and largest compartment of the ruminant digestive system. Coordinated muscular contractions of the rumen set up complex flows that mix the slurry of grass and saliva, filter digested particles for removal, and facilitate regurgitation and burping. Here you see the shape of a sheep rumen reconstructed from CT scans and overlaid with bright colours from computer simulations depicting the flow and mixing of the grass inside. http://art-of-bioeng.squarespace.com/rat-liver-atlas daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630373546-CJUDXXSESDPLWVR9MVXY/22-Harvey.jpg Rat Liver Atlas Rat Liver Atlas Dr Harvey Ho, Prof Uta Dahmen, Prof Peter Hunter An in silico rat liver atlas has been constructed from the micro-CT images of an explanted rat liver. The atlas consists of the parametric mesh of four liver lobes and large blood vessels. The atlas can be used in a number of physiological simulations. http://art-of-bioeng.squarespace.com/picassos-echo daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631465493-SH2NGXS979EGT6S1TKJ8/27-Debbie.jpg Picasso's Echo Picasso's Echo Debbie Zhao, Gina Quill, Craig McDougal Echocardiography, or simply ‘echo’, is notorious for its blurry, fuzzy, and at times even hopeless images. Yet, it remains at the frontline of cardiac diagnostics. As a non-invasive, highly accessible tool, echo relies on sound waves which bounce off the heart walls to create a live image. The repetition of the echocardiogram symbolises its ubiquity, while its organisation creates disorientation and perhaps confusion - as is at times experienced by those who are tasked with analysing such images. http://art-of-bioeng.squarespace.com/networks-in-the-heart daily 0.75 2020-11-20 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630538809-4J4BNP8JPQWM29O2CSVP/10-Bruce.jpg Networks in the Heart Networks in the Heart Prof Bruce Smaill, Dr Gregory Sands, Dr Jesse Ashton, Dr David Baddeley, Dr Mark Trew, Christine Sy, Vibujithan Vigneshwaran The heart consists of interconnected networks of cardiac muscle cells, blood vessels and nerves. Novel imaging methods developed at the ABI are being used to visualise these 3D networks in the human heart. This image shows the arrangement of cardiac muscle cells within the wall of the left ventricle. Groups of muscle cells are coloured yellow, individual muscle cells are red, and the green parts are blood vessels, connective tissue and fat cells. This project was supported by a grant from the Leducq Foundation. http://art-of-bioeng.squarespace.com/neapolitan-lamb-leg daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630948169-S0W49J64VKRJRXSXVZL6/25-Geoffry.jpg Neapolitan Lamb Leg Neapolitan Lamb Leg Dr Geoffrey Handsfield, Leo Dang, Salim Bin Ghouth, Randika Perera, Dr Samantha Holdsworth What's more Kiwi than a leg of lamb and advanced MRI? We mapped fractional anisotropy of diffusion tensors in the muscle tissue using MRI, revealing different muscle groups in the lamb leg, in technicolor detail. http://art-of-bioeng.squarespace.com/sugar-candy-lungs daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597627558160-UFWUXMPUBKWU58472LSG/01-Joyce.jpg Sugar Candy Lungs Sugar Candy Lungs Joyce John This precious pair of organs, vacuum-packed within the thoracic cavity, are responsible for oxygenating blood and removing carbon dioxide for the whole body. The volume of the tissues contained within is only about 3 litres but the surface area is approximately enough to cover a tennis court. The lung tissues can be scarred or remodelled by various diseases. The scarred tissues can be seen using computed tomography. They form ‘artistic patterns’ which can be distinguished from the normal tissue. Here, the sugar-candy-coloured tissues are scarred due to idiopathic pulmonary fibrosis - the brighter the pink, the more scarring. http://art-of-bioeng.squarespace.com/breathtaking daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597628134658-NTAPRX2QUDSJ9JTKCUL9/30-Sam.jpg Breathtaking Breathtaking Sam Richardson, Toby Jackson After careful dissection from a rat, the left lobe of the lungs was fixed and imaged using a micro computed tomography system. This image is the result of stitching together 6 individual radiographs, showing the microstructure of the lungs airways. To obtain an initial estimate of the 3D shape of the lungs, after stereoscopic imaging, lungs were fixed and imaged using a Bruker SkyScan 1272, micro-CT scanner. Fixing was achieved by inflating the lungs with Glutaraldehyde, which effectively kills the living cells in the lung, leaving behind the cross-linked structural proteins. Tissue samples fixed in glutaraldehyde are extensively cross-linked, providing excellent ultrastructural stiffening that maintains the structure of the alveoli, enabling imaging with microCT. http://art-of-bioeng.squarespace.com/the-camel-within daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597629421162-8D0ZDR4B7ML5VTVS3JKV/32-Zohreh.jpg The Camel Within The Camel Within Zohreh Ekhlasi, Mahyar Osanlouy, Dane Gerneke, Janet Keast, Peregrine Osborne This is a section from a very high resolution microCT image of a urinary bladder tissue. The bladder organ contains layers of dense, smooth muscle cells, and these cells communicate using specialised neurons. A detailed map of theses neurons is required for a better understanding of how the bladder is regulated and controlled - to generate this map, careful imaging and modelling are needed. In this image, interestingly enough, everything is arranged in such a way that it resembles the face of a camel. http://art-of-bioeng.squarespace.com/gallery-2020 daily 0.75 2024-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384320479-VN3W75RSMDWA2RBQTR2S/31-Sam.jpg Gallery 2020 Pleural https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384143039-WUPTD3YT5UPW3V7Z9KQ1/10-Bruce.jpg Gallery 2020 Networks in the Heart https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383415644-EC3CSK272VJ0YA61MDYR/27-Debbie.jpg Gallery 2020 Picasso's Echo https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384198617-BDGFY87KX87U2797C2UW/22-Harvey.jpg Gallery 2020 Rat Liver Atlas https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383099542-YTKXXQKY8RSWBK43ZHHZ/01-Joyce.jpg Gallery 2020 Sugar Candy Lungs https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383311084-DNDUPQS0AFUL02L6BYTO/33-Nazanin.jpg Gallery 2020 Blossoming Embryo https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383640651-G90NONYYQ6E8PTQN6HBU/34-Mahyar.jpg Gallery 2020 Lady and the Moon https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383455406-4K1URV0HR0JA94GS1KT7/20-Zahra.jpg Gallery 2020 The Enchanted Forest https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597632537525-FYNIOUIOT9BM43RWS8YR/image-asset.jpeg Gallery 2020 Into the Unknown https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597632572383-8I2DLGIOMLNDXD5RP02O/ALien.jpg Gallery 2020 Alien Lungs https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383665469-GUCDGM2N7FK0HCTE6A8K/32-Zohreh.jpg Gallery 2020 The Camel Within https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383253255-1HYTEVEEX4Y2H1380ZVZ/17-Vijay.jpg Gallery 2020 Anchor https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383174583-AQOHHLQTHVE24RZ276QO/05-Maryam.jpg Gallery 2020 Bird Brain https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383399169-29WTADMJ2KFAQW27Y76X/temp.png Gallery 2020 99 Red Balloons https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383886502-9NWG2DWBGWO0GXMM677F/08-Vinod.jpg Gallery 2020 Sheep Shape https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383847575-64C3T0SVINFYGX83EX07/03-Haribalan.jpg Gallery 2020 Lung Tissue Platter https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383224739-EPRTYNR33PWY03S9RJBY/12-Dane-Bamboo.png Gallery 2020 Skewed https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384293577-R6FBAAAP20XGDMQZWT69/25-Geoffry.jpg Gallery 2020 Neapolitan Lamb Leg https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383702603-8OY2GQ0P8073WCYBFRE9/21-Geoffry.jpg Gallery 2020 Googly Thighs https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384036355-2W25F8S4GBFOJ84LAUBE/18-Vijay.jpg Gallery 2020 Life Tree https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383607888-WPTFLNRYZBYWXLU5JY32/28-Bryon.jpg Gallery 2020 Deflection Triptych https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383373408-UB4FQRLH8JN5O6XIRKTY/26-Ryo.jpg Gallery 2020 Blended Life https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383950880-CRIRJ5JZXRXPVPB8GV1D/13-Dane-crab.jpg Gallery 2020 Mask https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383864356-I9FJ86Q9U5JQP5HHQDIB/04-Yi-Han.jpg Gallery 2020 Europa https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383990331-AB3PJ5VE7IHO7F31ZXFV/14-Vibu.jpg Gallery 2020 Coronary Circulation https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597384259602-JT5U3TTI9AYG0TBKPVFY/image-asset.jpeg Gallery 2020 One Small Step https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383819456-G64WL98PL2407H31CK6K/02-Hamid.jpg Gallery 2020 Evolutional Neuroscience https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383288960-W0ZLZKZ395SD2WU2NFLO/30-Sam.jpg Gallery 2020 Breathtaking https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597383914435-G3G7W9WB8EDESAWAWACU/09-Jagir.jpg Gallery 2020 Gears of Life http://art-of-bioeng.squarespace.com/into-the-unknown daily 0.75 2020-08-17 http://art-of-bioeng.squarespace.com/one-small-step daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630482823-XY4C5WBADMV4VC1Q37LE/23-Ducan.jpg One Small Step One Small Step Duncan Bakke When we conduct research (like modelling human gait) the end result may feel anticlimactic. Fake legs taking fake steps. But each step is the culmination of thousands of hours of work from dozens of researchers. Each of the bones visible in this image were generated using a shape modelling workflow carefully crafted using models of hundreds of people. The steps were recorded after training from several people, themselves trained for years - simulated in an open-source engine that’s taken a decade to develop. A giant leap, composed of a million tiny motes of progress. All for this one small step. http://art-of-bioeng.squarespace.com/europa daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597629465012-CXRJQPFGTS3AZVV0BQKO/04-Yi-Han.jpg Europa Europa Yi-Han Wu Research is about pushing the boundaries of human knowledge, but because it is uncertain by nature one can never predict experimental outcomes with absoluteness. Biological tests come with risks that are unfamiliar to generic engineering, yet sometimes that risk produces something beautiful and unpredictable. It’s like the view of the Gods as we look down the microscope. http://art-of-bioeng.squarespace.com/alien-lungs daily 0.75 2020-08-26 http://art-of-bioeng.squarespace.com/gallery-2015 daily 0.75 2024-09-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1450319166086-TNAJTLBPTI20B0ZF6U2J/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236692539-MOUU4ELDSUTPVGW99EMX/MEM_spider.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236111953-7YETKS65KWG88OF81WKY/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443743722888-F2OMLJ8A8IOVUIBNMQLF/Hues_of_Performance.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443742574878-V60FCZITFIT9HMK0TBPF/Clock_of_Life.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236902905-PFD66988HDMEKL1BRTS9/Re-entry.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236429897-8AN4SJ22Q4H3PLIOCPZX/Rat_Alveoli.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1449562861233-R1IWWR4ZUHL5ETEGA3IF/RabbitHeart_website_square.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236816147-O14R5STEMSAD5RHBDEEC/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236841461-18AHNAZ0DKGMPLWIZCY1/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1445229442295-UC0RD6181EHUABQQ84R5/starlight Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236879127-2U3BKX9SNU1UQDVYIOVH/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443577466849-XS9LEXTXKPRTXBNGGRRM/ICC_network.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443581326793-F1WDA02X94SRVCMPHFGB/Kaleidoscopic_3D_website.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443656836778-TIJ0EKFX0R8U6YQ1A1IX/temp.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443576852857-CDX657RJL4SV0KWHPS38/temp.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236181129-NI5YPAGAC4AIG5HWSFUL/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443744521362-38DGADR9KLWZCY7JCZPW/Micro_Electronics.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236225999-MEPOQFM5WZ9U9D2J7QXF/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443178230092-3TUH91HFEOO00E8J4RV1/Creeping+fingers+of+arthritis Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236338825-IVB35BFK83A8UX7CNOQG/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443237033438-OCV12DGBDNHS7IIZHVRT/image-asset.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443236748672-7GP823RCPJXPPQZBDWFX/Muscles_and_Bones.png Gallery 2015 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1443580792650-CND5LS43MTCDR7E3NL8W/image-asset.png Gallery 2015 http://art-of-bioeng.squarespace.com/evolutional-neuroscience daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631242209-WYPFC4Y3RHJ4DJ2NRLP8/02-Hamid.jpg Evolutional Neuroscience Evolutional Neuroscience Dr Hamid Abbasi The brain… known to be one of the most complex scientific-puzzles, which to date, neuroscience has only been able to partially discover its mysterious biological dynamic. Prognostic biomarkers of hypoxic-Ischemic brain injury in the form of EEG waveforms are propagated from the deeper brain structures and emerge only during a ~6 hour window of opportunity, after birth. Early diagnosis of these electric potentials in the neonatal EEG can help in a well-timed administration of neuroprotective protocols and improve outcomes. Our research team has developed robust deep machine-learning schemes to automatically identify these subtle waveforms in real-time before it is too late. http://art-of-bioeng.squarespace.com/coronary-circulation daily 0.75 2020-11-20 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631333965-GWK6C1959FTTB3G96SDM/14-Vibu.jpg Coronary Circulation Coronary Circulation Vibujithan Vigneshwaran, Prof Bruce Smaill, Dr Gregory Sands, Prof Nic Smith, Christine Sy An uninterrupted supply of oxygenated blood is required for optimum functionality of the heart - this is provided by coronary circulation. With the help of novel imaging techniques developed at the ABI, high resolution 3D images of the coronary network have been obtained, at an unprecedented scale. This macro-micro reconstruction of the coronary vessel network is showcased here. Professor Bruce Smaill and Dr Gregory Sands were supported by a grant from the Leducq Foundation. http://art-of-bioeng.squarespace.com/deflection-triptych daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630997339-J0ND4GM2AQHG0AJWJVBH/28-Bryon.jpg Deflection Triptych Deflection Triptych Dr Bryon Wright, Dixon Leung ABI’s Implantable Devices Group is developing novel MEMs pressure sensors. These images show three views of sensor performance – at best they should be identical. The lefthand image is a beautiful mistake generated when computer-aided modelling software interpolated spurious data. The centre image represents a model result that can be used to predict sensor performance. The righthand image represents a necessary view of reality: measured surface-shape data that is non-ideal and a challenge to interpret. http://art-of-bioeng.squarespace.com/lung-tissue-platter daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630853417-Y96IRQZYJWGK5FJD99BU/03-Haribalan.jpg Lung Tissue Platter Lung Tissue Platter Dr Haribalan Kumar, Grace Tawhai, Toby Jackson, Dane Gerneke High resolution micro-CT images of mouse lung tissue reveals the complex inner network of airway and alveolar structure. Different staining has produced stunning colour patterns. http://art-of-bioeng.squarespace.com/bird-brain daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597627707553-3GPNQQW0FPH3PUCDULQW/05-Maryam.jpg Bird Brain Bird Brain Maryam Tayebi Billions of neural fibers in your brain act as a relay to coordinate communication between different regions. Thanks to an advanced medical imaging technique - tractography - these fiber tracts can be visualized in a unique fashion. Just by slightly changing your view, you can find the extraordinary patterns that these fibers are making in your brain. http://art-of-bioeng.squarespace.com/blended-life daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597627979109-I7CUA4DNBFBUCUKPHFPW/26-Ryo.jpg Blended Life Blended Life Ryo Hajika, Philip Schmidt, Attila Reiss, Robert Duerichen, Claus Marberger, Kristof Van Laerhoven, Kenichi Yoneda The interplay between our various senses and how our brain processes them is what creates our emotions. We can analyse physiological signals using computer to understand human emotions better. “Blended Life” illustrates the dynamism of our vital signs. This two-dimensional visualization shows few key physiological signals (arm movement, heartbeat, skin conductance) gathered with an Empatica E4 sensor wristband, drawn with computer software that simulates water colour paint. http://art-of-bioeng.squarespace.com/skewed daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597628242869-7KPZBXCXH2F644TVUSZ8/12-Dane-Bamboo.png Skewed Skewed Dane Gerneke The cell structure of bamboo skewers makes a good test object for checking MicroCT image quality, as there is good contrast and fine details. This artistic rendition of 3D visualisation illustrates that perspective can change how samples appear. In this instance, the perspective is wildly distorted, as the original sample was a bunch of skewers parallel to each other. It is the same effect seen when using a wide angle or telephoto camera lenses. http://art-of-bioeng.squarespace.com/googly-thighs daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631411138-D2KKSOUALL18AH9FXJ1A/21-Geoffry.jpg Googly Thighs Googly Thighs Dr Geoffrey Handsfield, Sumedh Tulpule, Dr Julie Choisne, and Prof Thor Besier We started with a dataset of CT images of human legs; noticing the curve of the exam table under the legs looked like a smile, and remarking that the femurs looked kind of like eyes. All of a sudden we were looking upon a dataset of cute googly eyed (thighed?) faces. Different colormaps were utilized from the Matplotlib Python library. Inspired by the Marilyn Monroe series by Andy Warhol. http://art-of-bioeng.squarespace.com/gears-of-life daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597630903313-T5BTX2TJEN93YN4R1SI1/09-Jagir.jpg Gears of Life Gears of Life Dr Jagir Hussan, Prof Peter Hunter The human microbiome, an integral organ of the human body, manifests through a myriad of interactions - often viewed as a complex network of microorganisms. A mechanistic view reveals their role in maintaining a healthy life despite the demands of a lifestyle - just like the gears in an automobile help maneuver the demands of the road. http://art-of-bioeng.squarespace.com/blossoming-embryo daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631372026-WPCNE7TIDOF0Q4GD0Q6H/33-Nazanin.jpg Blossoming Embryo Blossoming Embryo Nazanin Ebrahimi, Mahyar Osanlouy, Dane Gerneke, Prof Peter Hunter Isn’t it beautiful to picture a baby coming to this world like how a flower blossoms? To study and model the development of the heart before birth, we carefully harvest rat embryos at the early days of gestation, through a very challenging experimental procedure. Various imaging techniques are used to capture the structural and functional dynamics of the heart tissue at different biological levels (from cell to whole organism) while ensured the integrity of the whole embryo remained intact. This 3D microCT image shows a rare moment when the embryo is held within the amniotic sac, hanging from the placenta, resembling a blossom beginning its life. http://art-of-bioeng.squarespace.com/lady-and-the-moon daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597629360706-VKOHNBXCXHTW35UYDLZY/34-Mahyar.jpg Lady and the Moon Lady and the Moon Mahyar Osanlouy, Nazanin Ebrahimi, Prof Peter Hunter This is a confocal microscopy image section of a chicken embryonic cells of a growing heart (red), its surrounding tissue (green), and the cellular nuclei (blue). To us, this slice resembles a lady (heart) sitting under a tree (surrounding tissue) with the moon (which is actually an image artifact) shining at night! http://art-of-bioeng.squarespace.com/pleural daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597629306580-30DE981F4JS60U19BG35/31-Sam.jpg Pleural Pleural Sam Richardson, Toby Jackson, Thiranja Prasad Babarenda Gamage The view of an inflated rat lung, from a single camera. Views from all 12 cameras in the calibrated stereo camera system can be used to reconstruct the external surface of the excised lung across a range of pressures. http://art-of-bioeng.squarespace.com/anchor daily 0.75 2020-08-17 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597627796102-CVLFM0QTMSKFQJQ53AJV/17-Vijay.jpg Anchor Anchor Vijayalakshmi Srinivasan, Dane Gerneke, Dr Alys Clark, Dr Jo James The placenta is a multi-tasker that supports the baby’s life inside the womb until birth. With the help of Micro-CT imaging, even the smallest fetal capillaries are visualized so we can look more closely into placental pathologies. It is fascinating to see a temporary organ with such complex vasculature, doing everything it can for a successful pregnancy. http://art-of-bioeng.squarespace.com/the-enchanted-forest daily 0.75 2020-08-26 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/1597631290555-B13TVQKNPZLVQKVVWFIX/20-Zahra.jpg The Enchanted Forest The Enchanted Forest Zahra Aghababaie, Kevin Jamart Within our stomach, a great wild and vivid forest shelters the life of millions of microscopic creatures. Each of these tiny beings works in harmony through sequences of organized contraction and crucial gurglings, to extract sugar and nutrients, the essential source of energy for our carbon-based existence. The coordination of this wonderful machinery is only possible thanks to an assembly of dedicated cells, orchestrating the ballet of digestion, by sending messages to the rest of the stomach. This kaleidoscope shows the miniscule world of the gut-brain in action. http://art-of-bioeng.squarespace.com/gallery-2024 daily 0.75 2024-10-01 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/2d1d3f83-d0f7-4ccf-9380-1e01bd2ba9ec/Tsz_Him_Chan.jpg Gallery 2024 Prostate Palette https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/34790a50-80aa-49cf-9cd0-5fd9c477e9ba/3--Small-but-mighty-mip-A3.jpg Gallery 2024 - Make it stand out Small But Mighty https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/0a8b8375-46a0-4c1a-bc3f-9d59cc37090b/Julia_Musgrave.jpg Gallery 2024 The Heart Within a Heart https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/7ef8338b-62a5-40cc-8310-6201fadc8bae/Dane_Gerneke_1.jpg Gallery 2024 A Miniature Orchid https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/cb44b7a8-c4b4-47d0-ad62-7d4716d10ce4/Roshan.jpg Gallery 2024 Arrhythmia (video) https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/55fa9dd3-ba4d-4d70-b140-da297a520ba8/Kelly_Burrowes.jpg Gallery 2024 Inhale: The Mosaic Within https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/81d9f13d-4f3b-407c-a571-950c91883e5d/Fung.jpg Gallery 2024 The Grape Breath (video) https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/53ecffcf-e8e3-43d7-9baa-9569b38abcf9/Vinod.jpg Gallery 2024 Flex and Squeeze https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/df5a4c0a-d8af-4703-b98e-a3e3163aa38c/Triana_Karnadipa_MovementBrainTemp.jpg Gallery 2024 Movement in Bloom https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/ee018464-1bbd-44df-99d7-0fe492a0fa11/Maryam_Rahmani_2.jpg Gallery 2024 Life Symphony https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/fe8e1563-b926-4339-91fa-30ec251745a2/fetal_atlas.png Gallery 2024 A Fetal Atlas https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/61dc7a2b-dba6-42ce-a319-a260c6ece454/Peng_Du.jpg Gallery 2024 Growing Ovomorphs https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/4d6f8f23-eef5-4526-ba72-9005b49645ac/Shashika_Munasingha.jpg Gallery 2024 Leap of Life https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/ddd0f5bb-8171-49b5-9de3-e7f3df5872a1/Anthony_Tang.jpg Gallery 2024 Connected Under the Waves https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/747e187e-ceb2-4a09-bbc5-74592c1bacf9/Skull.jpg Gallery 2024 Mind Unveiled (sculpture) https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/f61b929f-a5b4-4ff6-867b-29b37bf3b323/Alireza_Sharifzadeh-Kermani.jpg Gallery 2024 Intergalactic Brain https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/6d3a3f19-9d75-4f29-83b9-7aed5a74bcc1/TAMIL.jpg Gallery 2024 Symphony of Minds https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/4cfdbdda-d857-467a-93aa-0621f624a49c/Mathias_Roesler.jpg Gallery 2024 Ovarian Genie http://art-of-bioeng.squarespace.com/flex-and-squeeze daily 0.75 2024-09-23 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/53ecffcf-e8e3-43d7-9baa-9569b38abcf9/Vinod.jpg Flex and Squeeze Flex and Squeeze Ashlene Khoo, Sally Short, Ho-Fung Chan, Vinod Suresh with clinical input from Dr. Joseph Earles and Dr. Subhaschandra Shetty Non-cancerous thyroid tumours (goitre) can squeeze the airways and make breathing difficult. CT scans are used to assess goitre size and airway narrowing, but neck position can affect the assessment. Here, CT scans of the same patient taken in two positions are overlaid with computer simulations of the airflow. The airway shape was mapped from the CT scans and used to create physical models of the airway by 3D printing. http://art-of-bioeng.squarespace.com/heart-within-heart daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/24a84d88-2eb7-4e90-9bc2-b7b256735bda/Julia_Musgrave.jpg The Heart Within the Heart The Heart Within the Heart Julia Musgrave, Greg Sands, Marie-Louise Ward, June-Chiew Han, Andrew Taberner, Kenneth Tran This image shows a slice of a single piece of muscle, less than 1 mm across, from the inside of a human heart. The cells within this muscle were processed to make them fluorescent and visualise the structure. These muscle cells contract to make the heart beat, so we see that their function reflects the function of the organ they come from. Surprisingly, we see in this particular muscle that the cells also form a shape that mimics the organ they come from. Who knows, you may have a heart within your heart too! http://art-of-bioeng.squarespace.com/prostate-palette daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/2d1d3f83-d0f7-4ccf-9380-1e01bd2ba9ec/Tsz_Him_Chan.jpg Prostate Palette Prostate Palette Tsz Him Chan, Hayley Reynolds The prostate is a small, walnut-sized gland located just below the bladder in men. It produces fluids that are important for reproduction. The prostate doubles in size during puberty and starts growing again at around age 25 and beyond, which can sometimes lead to urination problems as men get older. Prostate cancer is one of the most common cancers in men. It can be tricky to detect early because it often affects only part of the prostate and doesn’t always show symptoms. In the artwork, cancerous tissues are shown on the left, coloured pink, and healthy tissues are on the right. Regular check-ups are especially important for men over 50 to stay healthy. http://art-of-bioeng.squarespace.com/the-grape-breath daily 0.75 2024-09-26 http://art-of-bioeng.squarespace.com/mind-unveiled daily 0.75 2024-09-30 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/747e187e-ceb2-4a09-bbc5-74592c1bacf9/Skull.jpg Mind Unveiled Mind Unveiled Callan Loomes, Hamid Abbasi, Alireza Sharifzadeh-Kermani, Maryam Tayebi For neurosurgeons, visualising a 3D representation of the brain from 2D slices while under the stress of surgery can quickly become a harrowing task. With state-of-the-art 3D printing techniques, we have the opportunity to revolutionise surgical planning, quickly transforming MRI scans of a patient into individual 3D phantom models which can be referred to in the operating theatre. Created from MRI data, this sculpture captures cerebral intricacies such as the main arterial blood supply in the brain, corpus callosum and occipitofrontal fasciculus. http://art-of-bioeng.squarespace.com/movement-in-bloom daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/df5a4c0a-d8af-4703-b98e-a3e3163aa38c/Triana_Karnadipa_MovementBrainTemp.jpg Movement in Bloom Movement in Bloom Triana Karnadipa This piece features brain pathways segmented into movement-related tracts that naturally resemble a vibrant, colourful flower. The myriad of colourful lines forms delicate, petal-like shapes. These tracts seem to bloom and shine with life, symbolizing the brain’s role in movement and growth, blending science and art in a radiant display. I’d like to give special thanks to Associate Professor Alan Wang for supporting me in this competition, and to Mishaim Malik for their help and support during the creation of the image. http://art-of-bioeng.squarespace.com/growing-ovomorphs daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/61dc7a2b-dba6-42ce-a319-a260c6ece454/Peng_Du.jpg Growing Ovomorphs Growing Ovomorphs Yu Luo, Jadranka Travas-Sejdic, Peng Du Sensors make contact with the body to record biological signals. Conventionally, sensor material is made of metal such as titanium, but through a chemical process called ‘doping’, non-conducting ‘plastic’ polymers can be made to carry electric current. This was the legacy bequeathed to us by the late New Zealand Nobel laureate Professor Alan MacDiarmid. Conducting polymer is now an exciting new frontier of material chemistry, with many applications for improved signal acquisition and biological capability. In this piece, the conducting polymer pillars are constructed using 3D printing, with a special technique to accurately engineer its formation with intricacy. http://art-of-bioeng.squarespace.com/intergalactic-brain daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/f61b929f-a5b4-4ff6-867b-29b37bf3b323/Alireza_Sharifzadeh-Kermani.jpg Intergalactic Brain Intergalactic Brain Alireza Sharifzadeh-Kermani, Jiantao Shen, Debbie Zhao, Kekeyan Nanthakumar, Stephen Creamer and the Animus Lab It is not an image of a nebula with a background of a starry night. In fact, it is the human brain displacement map with a background of MRI k-space - all MRIs are reconstructed from these starry-like images. My research revolves around creating computational models of the brain using MRI. We used the IXI dataset to create the k-space. http://art-of-bioeng.squarespace.com/connected-under-the-waves daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/ddd0f5bb-8171-49b5-9de3-e7f3df5872a1/Anthony_Tang.jpg Connected Under the Waves Connected Under the Waves Antony Tang, Wei-Ting Teo, Derek Orbaugh, Chen-Huan Lu Scuba diving opens the door to a mesmerizing underwater world, but it also comes with inherent risks. Our research is dedicated to enhancing diver safety through cutting-edge wearable technology. This piece showcases our innovative smart dive glove, designed to enable seamless underwater communication even without a direct line of sight. Accompanying it is our advanced physiological monitoring strap, which alerts nearby divers if the wearer experiences stress. The strap is equipped with hydrogel-based ECG sensors to monitor heart rate and a strain sensor to track breathing rate. For colder waters, the monitoring system is also available in a vest form, providing additional warmth to the diver. http://art-of-bioeng.squarespace.com/symphony-of-minds daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/6d3a3f19-9d75-4f29-83b9-7aed5a74bcc1/TAMIL.jpg Symphony of Minds Symphony of Minds Tamil Selvan Gunasekaran This piece illustrates the complex and beautiful interplay between cognitive and emotional states in collaborative settings. Inspired by the biosignals and behaviours of two people brainstorming in a video meeting, this artwork reveals the hidden patterns and rhythms of human interaction. Like a colourful symphony, their minds harmonise and clash, creating a beautiful and complex tapestry of connection. http://art-of-bioeng.squarespace.com/inhale-the-mosaic-within daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/55fa9dd3-ba4d-4d70-b140-da297a520ba8/Kelly_Burrowes.jpg Inhale: The Mosaic Within Inhale: The Mosaic Within Kelly Burrowes This piece captures the duality of respiration, blending the ephemeral flow of vape aerosol through the airways with the anatomical precision of human lung CT slices. The mosaic weaves together the visible and the invisible, creating a layered narrative that invites the viewer to explore the complex interplay between external substances and internal structures. By juxtaposing the allure of vapor with the fragility of lung tissue, this artwork encourages reflection on the unseen impact of every breath we take, highlighting both the beauty and vulnerability of the human body’s most vital function. http://art-of-bioeng.squarespace.com/leap-of-life daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/4d6f8f23-eef5-4526-ba72-9005b49645ac/Shashika_Munasingha.jpg Leap of Life Leap of Life Shashika Chamod, Kenneth Tran, Toan Pham, Marie Ward, Vijay Rajagopal Your heart tirelessly pumps over 10,000 litres of blood through your body daily. This incredible pump is powered by countless “frogs” (heart cells) working together to move your life forward. This artwork is a vibrant, three-colour segmented transmission electron microscopy image of a human heart cell, highlighting the distinct regions of mitochondria, myofibrils, and other cellular components. http://art-of-bioeng.squarespace.com/a-miniature-orchid daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/deb59104-4fbc-4f2b-b329-f988607cec77/Dane_Gerneke_1.jpg A Miniature Orchid A Miniature Orchid Dane Gerneke Delicate samples such as small flowers are challenging to image in Micro-CT as they can change shape when drying out over the long time (hours) while imaging. This 16mm orchid was successfully imaged using cryoMicro-CT with the sample frozen at -30°C. Maximum Intensity Projection (MIP) is a method to highlight bright internal structures. The bright lobes are the flowers pollen sacs hidden within the complex folds of the flower. It also reveals that the cells of the petals have denser strengthen borders to assist structural stiffness that maintain the flowers complex shape. Do you see a creature ? http://art-of-bioeng.squarespace.com/ovarian-genie daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/4cfdbdda-d857-467a-93aa-0621f624a49c/Mathias_Roesler.jpg Ovarian Genie Ovarian Genie Mathias Roesler, Dane Gerneke, Amy Garrett, Shawn Means, Leo Cheng, Alys Clark Rat ovaries, made up of a network of blood vessels, ducts, and many other things, can look like miniature brains. Micro-computed tomography lets us image the female gonad at a high resolution and peer through its curious structures in a 3D reconstruction. Adjusting colours, viewing angles, and transparency can create fabulous scenes. In this colourful display, the oviduct looks like a genie emanating between the uterine horn and the rest of the ovary. http://art-of-bioeng.squarespace.com/lifeline-symphony daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/ee018464-1bbd-44df-99d7-0fe492a0fa11/Maryam_Rahmani_2.jpg Lifeline Symphony Lifeline Symphony Maryam Rahmani This piece unveils the unseen rhythms essential for life, visualized through sophisticated labelling and high-resolution microscopy of key proteins that orchestrate the heartbeat. This artwork captures the vital interplay of these proteins, crucial for the heart’s rhythmic contractions. The intricate patterns within the cardiac cells weave a molecular symphony that echoes with the body’s pulse. This piece illuminates the beauty of the microscopic realm, where precise labelling and cutting-edge imaging techniques expose the subtle dance behind the heart’s constant beat, blending science and art in perfect harmony. http://art-of-bioeng.squarespace.com/a-fetal-atlas daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/fe8e1563-b926-4339-91fa-30ec251745a2/fetal_atlas.png A Fetal Atlas A Fetal Atlas Harvey Ho This artwork outlines the process of constructing a fetal atlas digitised from MRI images with a resolution of 0.5195 × 0.5195 × 2.8002 mm. The atlas includes detailed representations of major organs, blood vessels, and the umbilical cord of a 30-week-old fetus. It is provided in a neutral JSON format and can be accessed and downloaded from the following link: https://hwe001.github.io/fetus/ http://art-of-bioeng.squarespace.com/eye-of-the-arrhythmia daily 0.75 2024-10-01 http://art-of-bioeng.squarespace.com/small-but-mighty daily 0.75 2024-09-25 https://images.squarespace-cdn.com/content/v1/5605153be4b0612d66a8585b/34790a50-80aa-49cf-9cd0-5fd9c477e9ba/3--Small-but-mighty-mip-A3.jpg Small But Mighty Small But Mighty Lucille Chapuis, Dane Gerneke Crustaceans feature a striking and broad communicative repertoire, which depends on a variety of sensory organs and nervous circuitry allowing the detection of visual, acoustic, chemical and mechanosensory signals. Snapping shrimps are known for their wide range of social associations and behaviours. One of their first legs bears a voluminous claw with a complex snapping mechanism. The snap of the claw creates a cavitation bubble so loud that it is detectable for hundreds of meters underwater. In this image are particularly striking the visual system (compound eyes) and the statocyst complex (very bright), hypothesised to sense acoustic stimuli underwater.